Services
BioPredX develops technological platforms that evaluate the biological properties of novel biomolecules before experimental validation.
Less than 1% of all biological macromolecules have been experimentally characterised. Predicting the properties of novel biomolecules, particularly proteins and nucleic acids, opens new opportunities for innovation across biotechnology, biomedicine and precision medicine.
Rational protein design
Many proteins cannot reach their full industrial or biomedical potential because they lack sufficient stability under production, storage or use. BioPredX develops predictive technologies capable of identifying stabilising mutations and accelerating protein optimisation processes.
Protposer is our protein stabilisation platform. It proposes and prioritises specific mutations that enhance protein stability, making them easier to produce and preserve, and more resilient under demanding usage conditions. Protposer is available as a secure cloud-based SaaS platform and requires no local installation.
Applications
- Biopharmaceutical development
- Industrial enzyme optimisation
- Biocatalysis
- Biosensors
- Agricultural biotechnology
- Protein engineering
Protposer
Unlike conventional approaches that systematically evaluate all possible mutations of a protein, resulting in thousands of evaluations, Protposer identifies structurally vulnerable regions and proposes targeted stabilising mutations with a high probability of success.
Protposer is available either as an annual licence or through pay-per-use licences.
The platform provides:
- Stabilising mutation proposals
- Estimated probability of success for each mutation
- Structural and mechanistic rationale for each mutation
- Intuitive reports for experimental planning
Why Protposer?
- Greater efficiency: Reduces laboratory trials by 95%.
- ROI Maximization: Drastically decreases R&D costs.
- Commercial acceleration: Shortens biotech product development from years to months.
Looking to optimise proteins? Request access to our Protposer SaaS Demo at info@biopredx.com
About Protposer
Protposer: The web server that readily proposes protein stabilizing mutations with high PPV
Domain-guided engineering of a thermoresistant Vip3A toxin for enhanced functional robustness
Genetic Assessment
Next-generation sequencing (NGS) technologies allow affordable variant detection across the entire genome. However, determining their medical relevance requires more reliable interpretation tools.
BioPredX has developed Globalpred, a platform to support the genetic interpretation of single nucleotide variants (SNVs) that delivers superior predictive capabilities compared to existing platforms.
Globalpred helps clinicians to interpret variant pathogenicity and uncovers potential molecular consequences, providing an intuitive report instantly. Globalpred can be deployed either on-premise or available in the cloud.
Applications
- Precision medicine
- Clinical decision support
- Rare disease diagnosis
- Genetic screening
- Newborn screening
Globalpred
Globalpred is our platform for the interpretation of human genetic variants. It facilitates the early diagnosis of genetic diseases and the interpretation of somatic mutations, enabling personalised treatments.
Globalpred is marketed as an annual licence for public and private hospitals, molecular diagnostic clinics, and healthcare professionals who require genetic diagnosis to improve their patients’ quality of life.
Why Globalpred?
- High-Reliability Clinical Support: Provides automated, intuitive reports with excellent statistical metrics of correct predictions, ready for medical decision-making.
- Flexibility and Data Security: Available as a cloud-based solution or for on-premises deployment, ensuring strict compliance with medical data privacy regulations (GDPR).
- Cost Efficiency: Reduces analysis time per patient and helps accelerate diagnosis, lowering overall healthcare costs.
Interested in learning more? Contact us at info@biopredx.com to request further information or to launch a pilot programme within your organisation.
About Globalpred
Choosing Variant Interpretation Tools for Clinical Applications: Context Matters
BRCA1- and BRCA2-specific in silico tools for variant interpretation in the CAGI 5 ENIGMA challenge
Explainable AI for Life Sciences
Every challenge is unique. BioPredX develops predictive models tailored to the specific needs of each project. We leverage explainable artificial intelligence to identify biological patterns and deliver transparent, robust, and actionable results.